Posterior reversible encephalopathy syndrome (PRES) after treatment with oxaliplatin and 5-fluorouracil.

Introduction Posterior reversible encephalopathy syndrome (PRES) is a rare disease with a diverse range of precipitants. The cause is not well understood. We report a case of PRES that occurred soon after exposure to oxaliplatin and 5-fluorouracil, in which the patient presented with mild symptoms and normal blood pressure, but progressed to a severe condition with associated hypertension. The patient required treatment on the intensive care unit but made a fast and remarkable recovery. We remind clinicians of the possibility of this rare syndrome in patients exposed to chemotherapeutic agents and question the role of hypertension in the etiology.